FUMARPROTOCETRARIC ACID AND GERANIIN WERE IDENTIFIED AS NOVEL INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS INFECTION IN VITRO

Fumarprotocetraric acid and geraniin were identified as novel inhibitors of human respiratory syncytial virus infection in vitro

IntroductionRespiratory syncytial virus (RSV) remains a major international public health concern.However, disease treatment is limited to preventive care with monoclonal antibodies and supportive care.In this study, natural products were screened to identify novel anti-RSV inhibitors.MethodsThe antiviral effect of 320 compounds on RSV in HEp-2 cel

read more

Large vesicle extrusions from C. elegans neurons are consumed and stimulated by glial-like phagocytosis activity of the neighboring cell

Caenorhabditis elegans neurons under stress can produce giant vesicles, several microns in diameter, called exophers.Current models suggest that exophers are neuroprotective, providing a mechanism for stressed neurons to eject toxic protein aggregates and organelles.However, little is known of the fate of the exopher Guide Base Set once it leaves t

read more


A new therapeutic proposal for brassiere strap groove correction with injectable hyaluronic acid: a case report

Brassiere strap groove is a common aesthetic deformity in women with breast hypertrophy, resulting from chronic pressure exerted by brassiere Drawers straps on the soft tissues over the trapezius muscle, causing local tissue depression.This condition is typically treated with fat grafting, often Battery Blanket performed simultaneously with breast

read more